csa analyzer (Technoclone gmbh)
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Csa Analyzer, supplied by Technoclone gmbh, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/csa+analyzer/csa+analyzer/pmc09743337-55-41-42
Average 90 stars, based on 1 article reviews
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1) Product Images from "Impact of different factor VIII inhibitor kinetic profiles on the inhibitor titer quantification using the modified Nijmegen–Bethesda assay"
Article Title: Impact of different factor VIII inhibitor kinetic profiles on the inhibitor titer quantification using the modified Nijmegen–Bethesda assay
Journal: Research and Practice in Thrombosis and Haemostasis
doi: 10.1002/rth2.12799
Figure Legend Snippet: Inhibition kinetics of different FVIII monoclonal antibodies at different concentrations (concentration‐related study). Different FVIII monoclonal antibodies (4A4, BO2C11, 2‐54, ESH‐8) were diluted and mixed with a consistent amount of FVIII (neat: 1 μg/ml); after incubation, the FVIII residual activity was measured using an OSA (A) and CSA (B). CSA, chromogenic substrate assay; FVIII, factor VIII; OSA, one‐stage clotting assay.
Techniques Used: Inhibition, Bioprocessing, Concentration Assay, Incubation, Activity Assay, Coagulation
Figure Legend Snippet: Inhibition kinetics of different FVIII monoclonal antibodies by time course (time‐related study). Different monoclonal FVIII antibodies (4A4, BO2C11, 2‐54, ESH‐8) were diluted and mixed with a consistent amount of FVIII. The inhibition reaction was stopped at different time points and the FVIII residual activity was measured using an OSA (A–D) and CSA (A, B, and D). CSA, chromogenic substrate assay; FVIII, factor VIII; OSA, one‐stage clotting assay.
Techniques Used: Inhibition, Bioprocessing, Activity Assay, Coagulation
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Inhibition:Article Title: Impact of different factor VIII inhibitor kinetic profiles on the inhibitor titer quantification using the modified Nijmegen–Bethesda assay Article Snippet: For the time‐related study, the reaction was stopped by shock freezing at −80°C after 0, 5, 10, 15, 30, 60, 90, 120, and 180 min. After thawing, FVIII residual activities were immediately measured using the OSA (Roche Diagnostics International Ltd) and Bioprocessing:Article Title: Impact of different factor VIII inhibitor kinetic profiles on the inhibitor titer quantification using the modified Nijmegen–Bethesda assay Article Snippet: For the time‐related study, the reaction was stopped by shock freezing at −80°C after 0, 5, 10, 15, 30, 60, 90, 120, and 180 min. After thawing, FVIII residual activities were immediately measured using the OSA (Roche Diagnostics International Ltd) and Concentration Assay:Article Title: Impact of different factor VIII inhibitor kinetic profiles on the inhibitor titer quantification using the modified Nijmegen–Bethesda assay Article Snippet: For the time‐related study, the reaction was stopped by shock freezing at −80°C after 0, 5, 10, 15, 30, 60, 90, 120, and 180 min. After thawing, FVIII residual activities were immediately measured using the OSA (Roche Diagnostics International Ltd) and Incubation:Article Title: Impact of different factor VIII inhibitor kinetic profiles on the inhibitor titer quantification using the modified Nijmegen–Bethesda assay Article Snippet: For the time‐related study, the reaction was stopped by shock freezing at −80°C after 0, 5, 10, 15, 30, 60, 90, 120, and 180 min. After thawing, FVIII residual activities were immediately measured using the OSA (Roche Diagnostics International Ltd) and Activity Assay:Article Title: Impact of different factor VIII inhibitor kinetic profiles on the inhibitor titer quantification using the modified Nijmegen–Bethesda assay Article Snippet: For the time‐related study, the reaction was stopped by shock freezing at −80°C after 0, 5, 10, 15, 30, 60, 90, 120, and 180 min. After thawing, FVIII residual activities were immediately measured using the OSA (Roche Diagnostics International Ltd) and Coagulation:Article Title: Impact of different factor VIII inhibitor kinetic profiles on the inhibitor titer quantification using the modified Nijmegen–Bethesda assay Article Snippet: For the time‐related study, the reaction was stopped by shock freezing at −80°C after 0, 5, 10, 15, 30, 60, 90, 120, and 180 min. After thawing, FVIII residual activities were immediately measured using the OSA (Roche Diagnostics International Ltd) and |
